Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HSD3B1	HGNC:5217 (HGNC) 3283 (Entrez Gene) 109715 (OMIM) HSD3B1 (Alliance of Genome Resources)	Chr1 p12	Chr1:119507198-119515058 (+) GRCh38	hypertension	P14060 (UniProt | EBI) NM_001328615 (RefSeq)
	HSD3B2	HGNC:5218 (HGNC) 3284 (Entrez Gene) 613890 (OMIM) HSD3B2 (Alliance of Genome Resources)	Chr1 p12	Chr1:119414931-119423035 (+) GRCh38	hypospadias	P26439 (UniProt | EBI) NM_000198 (RefSeq)
mouse	Hsd3b6	MGI:109598 (MGI) 15497 (Entrez Gene) Gene Tree Hsd3b6 (Alliance of Genome Resources)	Chr3 42.88 cM	Chr3:98712820-98721759 (-) GRCm39		15497 (NCBI Gene Model) O35469 (UniProt | EBI) NM_013821 (RefSeq)
rat	Hsd3b2	RGD:67377 (Rat Genome Database) 29632 (Entrez Gene) Hsd3b2 (Alliance of Genome Resources)	Chr2 q34			Q62878 (UniProt | EBI) NM_017265 (RefSeq)
zebrafish	hsd3b1	ZDB-GENE-081105-30 (Zebrafish Model Organism Database) 553532 (Entrez Gene) hsd3b1 (Alliance of Genome Resources)	Chr9			NP_001373226 (RefSeq) NM_001386297 (RefSeq)
	hsd3b2	ZDB-GENE-030828-2 (Zebrafish Model Organism Database) 373131 (Entrez Gene) hsd3b2 (Alliance of Genome Resources)	Chr20			NP_997962 (RefSeq) NM_212797 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.