Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	E2F5	HGNC:3119 (HGNC) 1875 (Entrez Gene) 600967 (OMIM) E2F5 (Alliance of Genome Resources)	Chr8 q21.2	Chr8:85177154-85217158 (+) GRCh38	prostate carcinoma	Q15329 (UniProt | EBI) NM_001083588 (RefSeq)
mouse	E2f5	MGI:105091 (MGI) 13559 (Entrez Gene) Gene Tree E2f5 (Alliance of Genome Resources)	Chr3 3.1 cM	Chr3:14643701-14671369 (+) GRCm39	hydrocephalus	ENSMUSG00000027552 (Ensembl Gene Model) ENSMUSP00000029069 (Ensembl) ENSMUST00000029069 (Ensembl)
rat	E2f5	RGD:621357 (Rat Genome Database) 116651 (Entrez Gene) E2f5 (Alliance of Genome Resources)	Chr2 q23			Q62814 (UniProt | EBI) NM_001398639 (RefSeq)
zebrafish	e2f5	ZDB-GENE-030828-3 (Zebrafish Model Organism Database) 402908 (Entrez Gene) e2f5 (Alliance of Genome Resources)	Chr2			NP_001184229 (RefSeq) NM_001197300 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.