Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CYP1B1	HGNC:2597 (HGNC) 1545 (Entrez Gene) 601771 (OMIM) CYP1B1 (Alliance of Genome Resources)	Chr2 p22.2	Chr2:38066973-38109902 (-) GRCh38	anterior segment dysgenesis 6 breast cancer buphthalmos hydrophthalmos lung squamous cell carcinoma Peters anomaly primary open angle glaucoma	Q16678 (UniProt | EBI) NM_000104 (RefSeq)
mouse	Cyp1b1	MGI:88590 (MGI) 13078 (Entrez Gene) Gene Tree Cyp1b1 (Alliance of Genome Resources)	Chr17 50.3 cM	Chr17:80014369-80022490 (-) GRCm39	buphthalmos	13078 (NCBI Gene Model) Q64429 (UniProt | EBI) NM_009994 (RefSeq)
rat	Cyp1b1	RGD:2460 (Rat Genome Database) 25426 (Entrez Gene) Cyp1b1 (Alliance of Genome Resources)	Chr6 q12			Q64678 (UniProt | EBI) NM_012940 (RefSeq)
zebrafish	cyp1b1	ZDB-GENE-030902-1 (Zebrafish Model Organism Database) 100150054 (Entrez Gene) cyp1b1 (Alliance of Genome Resources)	Chr13			NP_001139180 (RefSeq) NM_001145708 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.