Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GSTM1	HGNC:4632 (HGNC) 2944 (Entrez Gene) 138350 (OMIM) GSTM1 (Alliance of Genome Resources)	Chr1 p13.3	Chr1:109687814-109709039 (+) GRCh38	acute chest syndrome acute lymphoblastic leukemia acute myeloid leukemia aggressive periodontitis allergic disease angle-closure glaucoma aplastic anemia asbestosis asphyxia neonatorum asthma atopic dermatitis autistic disorder breast cancer bronchopulmonary dysplasia cataract cervical cancer cervix carcinoma cholangiocarcinoma chronic obstructive pulmonary disease colorectal adenocarcinoma colorectal adenoma colorectal cancer colorectal carcinoma congenital heart disease coronary artery disease Crohn's disease cystic fibrosis diabetes mellitus diabetic retinopathy diffuse large B-cell lymphoma drug allergy end stage renal disease erythema nodosum esophageal atresia esophageal cancer esophagus adenocarcinoma esophagus squamous cell carcinoma exfoliation syndrome Fanconi anemia gastritis graft-versus-host disease head and neck cancer hepatic veno-occlusive disease hepatocellular carcinoma high grade glioma Hirschsprung's disease Hodgkin's lymphoma Human papillomavirus infectious disease hypospadias infectious mononucleosis inflammatory bowel disease keratosis Kuhnt-Junius degeneration larynx cancer leukopenia liver cirrhosis lung cancer lung disease lymphoid leukemia Lynch syndrome macular degeneration malignant astrocytoma malignant mesothelioma medulloblastoma movement disease multiple myeloma multiple sclerosis myelodysplastic syndrome myeloid leukemia optic neuritis oral cavity cancer oral mucosa leukoplakia oral squamous cell carcinoma oral submucous fibrosis osteonecrosis ovary epithelial cancer Parkinson's disease periodontitis polycythemia vera porphyria cutanea tarda pre-malignant neoplasm primary open angle glaucoma prostate cancer pterygium pulmonary emphysema pulmonary tuberculosis renal cell carcinoma rheumatoid arthritis schizophrenia senile cataract skin melanoma small intestine adenocarcinoma Stevens-Johnson syndrome stomach cancer systemic lupus erythematosus systemic scleroderma thalassemia toxic encephalopathy transitional cell carcinoma type 1 diabetes mellitus type 2 diabetes mellitus ulcerative colitis urinary bladder cancer urticaria	P09488 (UniProt | EBI) NM_000561 (RefSeq)
	GSTM5	HGNC:4637 (HGNC) 2949 (Entrez Gene) 138385 (OMIM) GSTM5 (Alliance of Genome Resources)	Chr1 p13.3	Chr1:109711751-109775428 (+) GRCh38	uterine fibroid	P46439 (UniProt | EBI) NM_000851 (RefSeq)
mouse	Gstm2	MGI:95861 (MGI) 14863 (Entrez Gene) Gene Tree Gstm2 (Alliance of Genome Resources)	Chr3 46.83 cM	Chr3:107889018-107893736 (-) GRCm39		14863 (NCBI Gene Model) P15626 (UniProt | EBI) NM_008183 (RefSeq)
rat	Gstm2	RGD:2756 (Rat Genome Database) 24424 (Entrez Gene) Gstm2 (Alliance of Genome Resources)	Chr2 q34			P08010 (UniProt | EBI) NM_177426 (RefSeq)
zebrafish	gstm.1	ZDB-GENE-030911-2 (Zebrafish Model Organism Database) 324366 (Entrez Gene) gstm.1 (Alliance of Genome Resources)	Chr8			NP_997841 (RefSeq) NM_212676 (RefSeq)
	gstm.2	ZDB-GENE-080218-30 (Zebrafish Model Organism Database) 571365 (Entrez Gene) gstm.2 (Alliance of Genome Resources)	Chr8			NP_001103586 (RefSeq) NM_001110116 (RefSeq)
	gstm.3	ZDB-GENE-050309-24 (Zebrafish Model Organism Database) 568744 (Entrez Gene) gstm.3 (Alliance of Genome Resources)	Chr8			NP_001156323 (RefSeq) NM_001162851 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.