Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EGFR	HGNC:3236 (HGNC) 1956 (Entrez Gene) 131550 (OMIM) EGFR (Alliance of Genome Resources)	Chr7 p11.2	Chr7:55019017-55211628 (+) GRCh38	breast carcinoma bronchiolo-alveolar adenocarcinoma colorectal cancer inflammatory bowel disease lung adenocarcinoma lung cancer lung non-small cell carcinoma pancreatic cancer prostate cancer pulmonary tuberculosis	P00533 (UniProt | EBI) NM_001346897 (RefSeq)
mouse	Egfr	MGI:95294 (MGI) 13649 (Entrez Gene) Gene Tree Egfr (Alliance of Genome Resources)	Chr11 9.41 cM	Chr11:16702203-16868158 (+) GRCm39	aortic valve disease Coronavirus infectious disease	ENSMUSG00000020122 (Ensembl Gene Model) ENSMUSP00000020329 (Ensembl) ENSMUST00000020329 (Ensembl)
rat	Egfr	RGD:2543 (Rat Genome Database) 24329 (Entrez Gene) Egfr (Alliance of Genome Resources)	Chr14 q22			NP_001380636 (RefSeq) NM_031507 (RefSeq)
zebrafish	egfra	ZDB-GENE-030918-1 (Zebrafish Model Organism Database) 378478 (Entrez Gene) egfra (Alliance of Genome Resources)	Chr2			NP_919405 (RefSeq) NM_194424 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.