Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ERBB4	HGNC:3432 (HGNC) 2066 (Entrez Gene) 600543 (OMIM) ERBB4 (Alliance of Genome Resources)	Chr2 q34	Chr2:211375717-212538841 (-) GRCh38	amyotrophic lateral sclerosis type 19 colorectal cancer esophagus squamous cell carcinoma hepatocellular carcinoma lung adenocarcinoma	Q15303 (UniProt | EBI) NM_001042599 (RefSeq)
mouse	Erbb4	MGI:104771 (MGI) 13869 (Entrez Gene) Gene Tree Erbb4 (Alliance of Genome Resources)	Chr1 33.8 cM	Chr1:68071345-69147218 (-) GRCm39		ENSMUSG00000062209 (Ensembl Gene Model) ENSMUSP00000112713 (Ensembl) ENSMUST00000119142 (Ensembl)
rat	Erbb4	RGD:620486 (Rat Genome Database) 59323 (Entrez Gene) Erbb4 (Alliance of Genome Resources)	Chr9 q32-q33			Q62956 (UniProt | EBI) NM_021687 (RefSeq)
zebrafish	erbb4a	ZDB-GENE-030918-4 (Zebrafish Model Organism Database) 100007677 (Entrez Gene) erbb4a (Alliance of Genome Resources)	Chr1			NP_001137223 (RefSeq) NM_001143751 (RefSeq)
	erbb4b	ZDB-GENE-030918-5 (Zebrafish Model Organism Database) 569836 (Entrez Gene) erbb4b (Alliance of Genome Resources)	Chr9			XP_009303149 (RefSeq)
	si:ch73-383l1.1	ZDB-GENE-121214-64 (Zebrafish Model Organism Database) 101885162 (Entrez Gene) si:ch73-383l1.1 (Alliance of Genome Resources)	Chr1			XP_068077088 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.