Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

 

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IGHV1-24	HGNC:5551 (HGNC) 28467 (Entrez Gene) IGHV1-24 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:106276546-106277043 (-) GRCh38		A0A0C4DH33 (UniProt | EBI)
	IGHV1-45	HGNC:5553 (HGNC) 28466 (Entrez Gene) IGHV1-45 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:106506996-106507491 (-) GRCh38		A0A0A0MS14 (UniProt | EBI)
	IGHV1-69-2	HGNC:5562 (HGNC) 28458 (Entrez Gene) IGHV1-69-2 (Alliance of Genome Resources)	Chr14 q32.33	Chr14:106737110-106737547 (-) GRCh38		A0A0G2JMI3 (UniProt | EBI)
mouse	Ighv1-12	MGI:3646284 (MGI) 629860 (Entrez Gene) Gene Tree Ighv1-12 (Alliance of Genome Resources)	Chr12 62.41 cM	Chr12:114579470-114579763 (-) GRCm39		629860 (NCBI Gene Model) A0A0A6YXJ9 (UniProt | EBI) M17953 (GenBank | ENA | DDBJ)
zebrafish	ighv2-1	ZDB-GENE-040514-2 (Zebrafish Model Organism Database) 100535575 (Entrez Gene) ighv2-1 (Alliance of Genome Resources)	Chr3
	ighv2-2	ZDB-GENE-030924-5 (Zebrafish Model Organism Database) 378757 (Entrez Gene) ighv2-2 (Alliance of Genome Resources)	Chr3
	ighv4-1	ZDB-GENE-040514-6 (Zebrafish Model Organism Database) 554306 (Entrez Gene) ighv4-1 (Alliance of Genome Resources)	Chr3

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.