Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AKT2	HGNC:392 (HGNC) 208 (Entrez Gene) 164731 (OMIM) AKT2 (Alliance of Genome Resources)	Chr19 q13.2	Chr19:40230317-40285536 (-) GRCh38	endometrial cancer hypoglycemia hypoinsulinemic hypoglycemia with hemihypertrophy ovarian carcinoma prostate adenocarcinoma prostate cancer prostate carcinoma type 2 diabetes mellitus	P31751 (UniProt | EBI) NM_001243028 (RefSeq)
mouse	Akt2	MGI:104874 (MGI) 11652 (Entrez Gene) Gene Tree Akt2 (Alliance of Genome Resources)	Chr7 15.94 cM	Chr7:27290977-27340251 (+) GRCm39	polycystic ovary syndrome type 2 diabetes mellitus	11652 (NCBI Gene Model) Q60823 (UniProt | EBI) NM_001331108 (RefSeq)
rat	Akt2	RGD:2082 (Rat Genome Database) 25233 (Entrez Gene) Akt2 (Alliance of Genome Resources)	Chr1 q21			P47197 (UniProt | EBI) NM_017093 (RefSeq)
zebrafish	akt2	ZDB-GENE-031007-5 (Zebrafish Model Organism Database) 378972 (Entrez Gene) akt2 (Alliance of Genome Resources)	Chr18			NP_937789 (RefSeq) NM_198146 (RefSeq)
	akt2l	ZDB-GENE-040121-5 (Zebrafish Model Organism Database) 403146 (Entrez Gene) akt2l (Alliance of Genome Resources)	Chr10			NP_997980 (RefSeq) NM_212815 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.