Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SP4	HGNC:11209 (HGNC) 6671 (Entrez Gene) 600540 (OMIM) SP4 (Alliance of Genome Resources)	Chr7 p15.3	Chr7:21428043-21514822 (+) GRCh38	congenital heart disease dilated cardiomyopathy	Q02446 (UniProt | EBI) NM_001326543 (RefSeq)
mouse	Sp4	MGI:107595 (MGI) 20688 (Entrez Gene) Gene Tree Sp4 (Alliance of Genome Resources)	Chr12 63.48 cM	Chr12:118198668-118265175 (-) GRCm39	schizophrenia	ENSMUSG00000025323 (Ensembl Gene Model) ENSMUSP00000152603 (Ensembl) ENSMUST00000222314 (Ensembl)
rat	Sp4	RGD:3741 (Rat Genome Database) 25162 (Entrez Gene) Sp4 (Alliance of Genome Resources)	Chr6 q33			NP_036893 (RefSeq) NM_012761 (RefSeq)
zebrafish	sp4	ZDB-GENE-031202-3 (Zebrafish Model Organism Database) 387291 (Entrez Gene) sp4 (Alliance of Genome Resources)	Chr19			NP_956418 (RefSeq) NM_200124 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.