Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLR9	HGNC:15633 (HGNC) 54106 (Entrez Gene) 605474 (OMIM) TLR9 (Alliance of Genome Resources)	Chr3 p21.2	Chr3:52221080-52225645 (-) GRCh38	allergic bronchopulmonary aspergillosis asthma bronchiolitis obliterans cardiovascular system disease chronic kidney disease cystic fibrosis hepatitis B hepatitis C hepatocellular carcinoma IgA glomerulonephritis lupus nephritis proteinuria pulmonary tuberculosis systemic lupus erythematosus viral pneumonia	Q9NR96 (UniProt | EBI) NM_017442 (RefSeq)
mouse	Tlr9	MGI:1932389 (MGI) 81897 (Entrez Gene) Gene Tree Tlr9 (Alliance of Genome Resources)	Chr9 57.46 cM	Chr9:106099797-106104075 (+) GRCm39		81897 (NCBI Gene Model) Q9EQU3 (UniProt | EBI) NM_031178 (RefSeq)
rat	Tlr9	RGD:631352 (Rat Genome Database) 338457 (Entrez Gene) Tlr9 (Alliance of Genome Resources)	Chr8			NP_937764 (RefSeq) NM_198131 (RefSeq)
zebrafish	tlr9	ZDB-GENE-040219-10 (Zebrafish Model Organism Database) 403128 (Entrez Gene) tlr9 (Alliance of Genome Resources)	Chr8			NP_001124066 (RefSeq) NM_001130594 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.