Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLR3	HGNC:11849 (HGNC) 7098 (Entrez Gene) 603029 (OMIM) TLR3 (Alliance of Genome Resources)	Chr4 q35.1	Chr4:186068911-186088073 (+) GRCh38	asthma hepatitis B hepatitis C human immunodeficiency virus infectious disease liver cirrhosis primary immunodeficiency disease type 1 diabetes mellitus	O15455 (UniProt | EBI) NM_003265 (RefSeq)
mouse	Tlr3	MGI:2156367 (MGI) 142980 (Entrez Gene) Gene Tree Tlr3 (Alliance of Genome Resources)	Chr8 25.31 cM	Chr8:45848702-45864112 (-) GRCm39		142980 (NCBI Gene Model) Q99MB1 (UniProt | EBI) NM_126166 (RefSeq)
rat	Tlr3	RGD:735171 (Rat Genome Database) 364594 (Entrez Gene) Tlr3 (Alliance of Genome Resources)	Chr16 q11			NP_942086 (RefSeq) NM_198791 (RefSeq)
zebrafish	tlr3	ZDB-GENE-040219-7 (Zebrafish Model Organism Database) 403126 (Entrez Gene) tlr3 (Alliance of Genome Resources)	Chr1			NP_001013287 (RefSeq) NM_001013269 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.