Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HCRT	HGNC:4847 (HGNC) 3060 (Entrez Gene) 602358 (OMIM) HCRT (Alliance of Genome Resources)	Chr17 q21.2	Chr17:42184060-42185452 (-) GRCh38	heroin dependence narcolepsy	O43612 (UniProt | EBI) NM_001524 (RefSeq)
mouse	Hcrt	MGI:1202306 (MGI) 15171 (Entrez Gene) Gene Tree Hcrt (Alliance of Genome Resources)	Chr11 63.6 cM	Chr11:100652519-100653757 (-) GRCm39	narcolepsy	15171 (NCBI Gene Model) O55241 (UniProt | EBI) NM_010410 (RefSeq)
rat	Hcrt	RGD:2786 (Rat Genome Database) 25723 (Entrez Gene) Hcrt (Alliance of Genome Resources)	Chr10 q31			O55232 (UniProt | EBI) NM_013179 (RefSeq)
zebrafish	hcrt	ZDB-GENE-040324-1 (Zebrafish Model Organism Database) 613239 (Entrez Gene) hcrt (Alliance of Genome Resources)	Chr3			NP_001070860 (RefSeq) NM_001077392 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.