Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IGFBP3	HGNC:5472 (HGNC) 3486 (Entrez Gene) 146732 (OMIM) IGFBP3 (Alliance of Genome Resources)	Chr7 p12.3	Chr7:45912245-45921874 (-) GRCh38	Alzheimer's disease breast cancer inflammatory bowel disease prostate cancer transitional cell carcinoma Turner syndrome type 1 diabetes mellitus type 2 diabetes mellitus	P17936 (UniProt | EBI) NM_000598 (RefSeq)
mouse	Igfbp3	MGI:96438 (MGI) 16009 (Entrez Gene) Gene Tree Igfbp3 (Alliance of Genome Resources)	Chr11 4.75 cM	Chr11:7156086-7163923 (-) GRCm39		ENSMUSG00000020427 (Ensembl Gene Model) ENSMUSP00000020702 (Ensembl) ENSMUST00000020702 (Ensembl)
rat	Igfbp3	RGD:2874 (Rat Genome Database) 24484 (Entrez Gene) Igfbp3 (Alliance of Genome Resources)	Chr14 q21			P15473 (UniProt | EBI) NM_012588 (RefSeq)
zebrafish	igfbp3	ZDB-GENE-040412-1 (Zebrafish Model Organism Database) 403079 (Entrez Gene) igfbp3 (Alliance of Genome Resources)	Chr20			NP_991314 (RefSeq) NM_205751 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.