Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMEM106B	HGNC:22407 (HGNC) 54664 (Entrez Gene) 613413 (OMIM) TMEM106B (Alliance of Genome Resources)	Chr7 p21.3	Chr7:12211270-12243367 (+) GRCh38	hypomyelinating leukodystrophy 16	Q9NUM4 (UniProt | EBI) NM_018374 (RefSeq)
mouse	Tmem106b	MGI:1919150 (MGI) 71900 (Entrez Gene) Gene Tree Tmem106b (Alliance of Genome Resources)	Chr6 5.38 cM	Chr6:13069758-13089268 (+) GRCm39		71900 (NCBI Gene Model) Q80X71 (UniProt | EBI) NM_027992 (RefSeq)
rat	Tmem106b	RGD:1303037 (Rat Genome Database) 312132 (Entrez Gene) Tmem106b (Alliance of Genome Resources)	Chr4 q21			Q6AYA5 (UniProt | EBI) NM_001004267 (RefSeq)
zebrafish	tmem106ba	ZDB-GENE-040426-1336 (Zebrafish Model Organism Database) 393333 (Entrez Gene) tmem106ba (Alliance of Genome Resources)	Chr15			NP_956656 (RefSeq) NM_200362 (RefSeq)
	tmem106bb	ZDB-GENE-050913-37 (Zebrafish Model Organism Database) 566699 (Entrez Gene) tmem106bb (Alliance of Genome Resources)	Chr19			Q1LWC2 (UniProt | EBI) NM_001045052 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.