Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CLCNKA	HGNC:2026 (HGNC) 1187 (Entrez Gene) 602024 (OMIM) CLCNKA (Alliance of Genome Resources)	Chr1 p36.13	Chr1:16018875-16034050 (+) GRCh38	Bartter disease type 4b sensorineural hearing loss	P51800 (UniProt | EBI) NM_001257139 (RefSeq)
	CLCNKB	HGNC:2027 (HGNC) 1188 (Entrez Gene) 602023 (OMIM) CLCNKB (Alliance of Genome Resources)	Chr1 p36.13	Chr1:16040252-16057326 (+) GRCh38	Bartter disease type 3 Bartter disease type 4b Gitelman syndrome hypertension	P51801 (UniProt | EBI) NM_001165945 (RefSeq)
mouse	Clcnka	MGI:1329026 (MGI) 12733 (Entrez Gene) Gene Tree Clcnka (Alliance of Genome Resources)	Chr4 73.94 cM	Chr4:141111922-141126017 (-) GRCm39	nephrogenic diabetes insipidus	12733 (NCBI Gene Model) Q9WUB7 (UniProt | EBI) NM_024412 (RefSeq)
rat	Clcnka	RGD:68435 (Rat Genome Database) 79425 (Entrez Gene) Clcnka (Alliance of Genome Resources)	Chr5 q36			Q06393 (UniProt | EBI) NM_053327 (RefSeq)
zebrafish	clcnk	ZDB-GENE-040426-1379 (Zebrafish Model Organism Database) 393353 (Entrez Gene) clcnk (Alliance of Genome Resources)	Chr23			NP_956676 (RefSeq) NM_200382 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.