Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GGT1	HGNC:4250 (HGNC) 2678 (Entrez Gene) 612346 (OMIM) GGT1 (Alliance of Genome Resources)	Chr22 q11.23	Chr22:24583750-24629005 (+) GRCh38	gamma-glutamyl transpeptidase deficiency	P19440 (UniProt | EBI) NM_001032364 (RefSeq)
	GGT2P	HGNC:4251 (HGNC) 728441 (Entrez Gene) 137181 (OMIM) GGT2P (Alliance of Genome Resources)	Chr22 q11.21	Chr22:21207973-21259684 (-) GRCh38		P36268 (UniProt | EBI) NM_001351304 (RefSeq)
	GGT3P	HGNC:4252 (HGNC) 2679 (Entrez Gene) GGT3P (Alliance of Genome Resources)	Chr22 q11.21	Chr22:18773689-18791961 (-) GRCh38		A6NGU5 (UniProt | EBI)
	GGTLC1	HGNC:16437 (HGNC) 92086 (Entrez Gene) 612338 (OMIM) GGTLC1 (Alliance of Genome Resources)	Chr20 p11.21	Chr20:23985050-23988779 (-) GRCh38		Q9BX51 (UniProt | EBI) NM_178312 (RefSeq)
	GGTLC2	HGNC:18596 (HGNC) 91227 (Entrez Gene) 612339 (OMIM) GGTLC2 (Alliance of Genome Resources)	Chr22 q11.22	Chr22:22644614-22647898 (+) GRCh38		Q14390 (UniProt | EBI) NM_001391911 (RefSeq)
	GGTLC3	HGNC:33426 (HGNC) 728226 (Entrez Gene) 612340 (OMIM) GGTLC3 (Alliance of Genome Resources)	Chr22 q11.21	Chr22:18516338-18518166 (-) GRCh38		B5MD39 (UniProt | EBI) NM_001355479 (RefSeq)
mouse	Ggt1	MGI:95706 (MGI) 14598 (Entrez Gene) Gene Tree Ggt1 (Alliance of Genome Resources)	Chr10 38.55 cM	Chr10:75397438-75422034 (+) GRCm39		ENSMUSG00000006345 (Ensembl Gene Model) ENSMUSP00000006508 (Ensembl) ENSMUST00000006508 (Ensembl)
rat	Ggt1	RGD:2683 (Rat Genome Database) 116568 (Entrez Gene) Ggt1 (Alliance of Genome Resources)	Chr20			P07314 (UniProt | EBI) NM_053840 (RefSeq)
zebrafish	ggt1a	ZDB-GENE-040426-1388 (Zebrafish Model Organism Database) 393387 (Entrez Gene) ggt1a (Alliance of Genome Resources)	Chr8			NP_956709 (RefSeq) NM_200415 (RefSeq)
	ggt1b	ZDB-GENE-110408-13 (Zebrafish Model Organism Database) 569014 (Entrez Gene) ggt1b (Alliance of Genome Resources)	Chr10			XP_697468 (RefSeq)
	ggt1l2.1	ZDB-GENE-090312-32 (Zebrafish Model Organism Database) 100148732 (Entrez Gene) ggt1l2.1 (Alliance of Genome Resources)	Chr1			XP_068077069 (RefSeq)
	ggt1l2.2	ZDB-GENE-090312-37 (Zebrafish Model Organism Database) 566746 (Entrez Gene) ggt1l2.2 (Alliance of Genome Resources)	Chr1			XP_009294029 (RefSeq)
	si:ch73-59p9.2	ZDB-GENE-121214-48 (Zebrafish Model Organism Database) 101884069 (Entrez Gene) si:ch73-59p9.2 (Alliance of Genome Resources)	Chr1			XP_068077029 (RefSeq)
	si:ch73-236c18.3	ZDB-GENE-121214-50 (Zebrafish Model Organism Database) 794105 (Entrez Gene) si:ch73-236c18.3 (Alliance of Genome Resources)	Chr1			XP_068078273 (RefSeq)
	si:dkey-222h21.12	ZDB-GENE-090312-33 (Zebrafish Model Organism Database) 795959 (Entrez Gene) si:dkey-222h21.12 (Alliance of Genome Resources)	Chr1			XP_021333865 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.