Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNM1L	HGNC:2973 (HGNC) 10059 (Entrez Gene) 603850 (OMIM) DNM1L (Alliance of Genome Resources)	Chr12 p11.21	Chr12:32679200-32745650 (+) GRCh38	encephalopathy due to defective mitochondrial and peroxisomal fission 1 optic atrophy 5	O00429 (UniProt | EBI) NM_001278464 (RefSeq)
mouse	Dnm1l	MGI:1921256 (MGI) 74006 (Entrez Gene) Gene Tree Dnm1l (Alliance of Genome Resources)	Chr16 10.12 cM	Chr16:16130094-16176823 (-) GRCm39	dilated cardiomyopathy	ENSMUSG00000022789 (Ensembl Gene Model) ENSMUSP00000155155 (Ensembl) ENSMUST00000230980 (Ensembl)
rat	Dnm1l	RGD:620416 (Rat Genome Database) 114114 (Entrez Gene) Dnm1l (Alliance of Genome Resources)	Chr11 q23			O35303 (UniProt | EBI) NM_053655 (RefSeq)
zebrafish	dnm1l	ZDB-GENE-040426-1556 (Zebrafish Model Organism Database) 393896 (Entrez Gene) dnm1l (Alliance of Genome Resources)	Chr25			Q7SXN5 (UniProt | EBI) NM_200922 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.