Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC22A4	HGNC:10968 (HGNC) 6583 (Entrez Gene) 604190 (OMIM) SLC22A4 (Alliance of Genome Resources)	Chr5 q31.1	Chr5:132294394-132344190 (+) GRCh38	rheumatoid arthritis	Q9H015 (UniProt | EBI) NM_003059 (RefSeq)
mouse	Slc22a4	MGI:1353479 (MGI) 30805 (Entrez Gene) Gene Tree Slc22a4 (Alliance of Genome Resources)	Chr11 32.07 cM	Chr11:53873949-53918916 (-) GRCm39		ENSMUSG00000020334 (Ensembl Gene Model) ENSMUSP00000020586 (Ensembl) ENSMUST00000020586 (Ensembl)
rat	Slc22a4	RGD:621149 (Rat Genome Database) 64037 (Entrez Gene) Slc22a4 (Alliance of Genome Resources)	Chr10			Q9R141 (UniProt | EBI) NM_022270 (RefSeq)
zebrafish	slc22a4	ZDB-GENE-040426-1517 (Zebrafish Model Organism Database) 393822 (Entrez Gene) slc22a4 (Alliance of Genome Resources)	Chr21			NP_957143 (RefSeq) NM_200849 (RefSeq)
	slc22a21	ZDB-GENE-091118-62 (Zebrafish Model Organism Database) 799908 (Entrez Gene) slc22a21 (Alliance of Genome Resources)	Chr21			NP_001295487 (RefSeq) NM_001308558 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.