Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYL3	HGNC:7584 (HGNC) 4634 (Entrez Gene) 160790 (OMIM) MYL3 (Alliance of Genome Resources)	Chr3 p21.31	Chr3:46835110-46882182 (-) GRCh38	hypertrophic cardiomyopathy 8	P08590 (UniProt | EBI) NM_001406937 (RefSeq)
mouse	Myl3	MGI:97268 (MGI) 17897 (Entrez Gene) Gene Tree Myl3 (Alliance of Genome Resources)	Chr9 60.69 cM	Chr9:110592746-110598870 (+) GRCm39	osteoarthritis	17897 (NCBI Gene Model) P09542 (UniProt | EBI) NM_010859 (RefSeq)
rat	Myl3	RGD:3142 (Rat Genome Database) 24585 (Entrez Gene) Myl3 (Alliance of Genome Resources)	Chr8 q32			P16409 (UniProt | EBI) NM_012606 (RefSeq)
zebrafish	myl4	ZDB-GENE-050626-112 (Zebrafish Model Organism Database) 574004 (Entrez Gene) myl4 (Alliance of Genome Resources)	Chr3			NP_001020354 (RefSeq) NM_001025183 (RefSeq)
	myl13	ZDB-GENE-040426-1593 (Zebrafish Model Organism Database) 393488 (Entrez Gene) myl13 (Alliance of Genome Resources)	Chr2			NP_956810 (RefSeq) NM_200516 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.