Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDPK1	HGNC:8816 (HGNC) 5170 (Entrez Gene) 605213 (OMIM) PDPK1 (Alliance of Genome Resources)	Chr16 p13.3	Chr16:2537979-2603188 (+) GRCh38	prostate cancer	Q6A1A2 (UniProt | EBI) NM_001261816 (RefSeq)
	PDPK2P	HGNC:49897 (HGNC) 653650 (Entrez Gene) PDPK2P (Alliance of Genome Resources)	Chr16 p13.3	Chr16:2616453-2642490 (-) GRCh38
mouse	Pdpk1	MGI:1338068 (MGI) 18607 (Entrez Gene) Gene Tree Pdpk1 (Alliance of Genome Resources)	Chr17 12.23 cM	Chr17:24292654-24369898 (-) GRCm39		ENSMUSG00000024122 (Ensembl Gene Model) ENSMUSP00000099991 (Ensembl) ENSMUST00000102927 (Ensembl)
rat	Pdpk1	RGD:620307 (Rat Genome Database) 81745 (Entrez Gene) Pdpk1 (Alliance of Genome Resources)	Chr10 q12			O55173 (UniProt | EBI) NM_031081 (RefSeq)
zebrafish	pdpk1a	ZDB-GENE-061013-109 (Zebrafish Model Organism Database) 768202 (Entrez Gene) pdpk1a (Alliance of Genome Resources)	Chr3			NP_001070812 (RefSeq) NM_001077344 (RefSeq)
	pdpk1b	ZDB-GENE-040426-1820 (Zebrafish Model Organism Database) 403000 (Entrez Gene) pdpk1b (Alliance of Genome Resources)	Chr24			NP_991262 (RefSeq) NM_205699 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.