Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

 

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HPRT1	HGNC:5157 (HGNC) 3251 (Entrez Gene) 308000 (OMIM) HPRT1 (Alliance of Genome Resources)	ChrX q26.2-q26.3	ChrX:134460165-134520513 (+) GRCh38	HRPT-related hyperuricemia Lesch-Nyhan syndrome	P00492 (UniProt | EBI) NM_000194 (RefSeq)
mouse	Hprt1	MGI:96217 (MGI) 15452 (Entrez Gene) Gene Tree Hprt1 (Alliance of Genome Resources)	ChrX 29.31 cM	ChrX:52077014-52110536 (+) GRCm39	Lesch-Nyhan syndrome	ENSMUSG00000025630 (Ensembl Gene Model) ENSMUSP00000026723 (Ensembl) ENSMUST00000026723 (Ensembl)
rat	Hprt1	RGD:2826 (Rat Genome Database) 24465 (Entrez Gene) Hprt1 (Alliance of Genome Resources)	ChrX q36			P27605 (UniProt | EBI) NM_012583 (RefSeq)
zebrafish	hprt1	ZDB-GENE-040426-1918 (Zebrafish Model Organism Database) 406259 (Entrez Gene) hprt1 (Alliance of Genome Resources)	Chr14			NP_998151 (RefSeq) NM_212986 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.