Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SQSTM1	HGNC:11280 (HGNC) 8878 (Entrez Gene) 601530 (OMIM) SQSTM1 (Alliance of Genome Resources)	Chr5 q35.3	Chr5:179806393-179838078 (+) GRCh38	distal myopathy with rimmed vacuoles frontotemporal dementia and/or amyotrophic lateral sclerosis 3 neurodegeneration with ataxia, dystonia, and gaze palsy, childhood-onset Paget's disease of bone Paget's disease of bone 3	Q13501 (UniProt | EBI) NM_001142298 (RefSeq)
mouse	Sqstm1	MGI:107931 (MGI) 18412 (Entrez Gene) Gene Tree Sqstm1 (Alliance of Genome Resources)	Chr11 30.36 cM	Chr11:50090193-50101654 (-) GRCm39	Paget's disease of bone	ENSMUSG00000015837 (Ensembl Gene Model) ENSMUSP00000099835 (Ensembl) ENSMUST00000102774 (Ensembl)
rat	Sqstm1	RGD:69287 (Rat Genome Database) 113894 (Entrez Gene) Sqstm1 (Alliance of Genome Resources)	Chr10 q22			O08623 (UniProt | EBI) NM_175843 (RefSeq)
zebrafish	sqstm1	ZDB-GENE-040426-2204 (Zebrafish Model Organism Database) 406452 (Entrez Gene) sqstm1 (Alliance of Genome Resources)	Chr14			NP_001299842 (RefSeq) NM_213173 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.