Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ATF4	HGNC:786 (HGNC) 468 (Entrez Gene) 604064 (OMIM) ATF4 (Alliance of Genome Resources)	Chr22 q13.1	Chr22:39519695-39522686 (+) GRCh38	prostate carcinoma	P18848 (UniProt | EBI) NM_182810 (RefSeq)
mouse	Atf4	MGI:88096 (MGI) 11911 (Entrez Gene) Gene Tree Atf4 (Alliance of Genome Resources)	Chr15 37.85 cM	Chr15:80139385-80141742 (+) GRCm39		ENSMUSG00000042406 (Ensembl Gene Model) ENSMUSP00000105234 (Ensembl) ENSMUST00000109605 (Ensembl)
rat	Atf4	RGD:621863 (Rat Genome Database) 79255 (Entrez Gene) Atf4 (Alliance of Genome Resources)	Chr7 q34			Q9ES19 (UniProt | EBI) NM_024403 (RefSeq)
zebrafish	atf4a	ZDB-GENE-040426-2340 (Zebrafish Model Organism Database) 406514 (Entrez Gene) atf4a (Alliance of Genome Resources)	Chr6			Q6NW59 (UniProt | EBI) NM_213233 (RefSeq)
	atf4b	ZDB-GENE-070928-23 (Zebrafish Model Organism Database) 556410 (Entrez Gene) atf4b (Alliance of Genome Resources)	Chr3			NP_001096662 (RefSeq) NM_001103192 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.