Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DNM2	HGNC:2974 (HGNC) 1785 (Entrez Gene) 602378 (OMIM) DNM2 (Alliance of Genome Resources)	Chr19 p13.2	Chr19:10718055-10833488 (+) GRCh38	centronuclear myopathy 1 Charcot-Marie-Tooth disease dominant intermediate B lethal congenital contracture syndrome	P50570 (UniProt | EBI) NM_004945 (RefSeq)
mouse	Dnm2	MGI:109547 (MGI) 13430 (Entrez Gene) Gene Tree Dnm2 (Alliance of Genome Resources)	Chr9 7.79 cM	Chr9:21336204-21419055 (+) GRCm39	centronuclear myopathy cystic kidney disease microcytic anemia myopathy	ENSMUSG00000033335 (Ensembl Gene Model) ENSMUSP00000072199 (Ensembl) ENSMUST00000072362 (Ensembl)
rat	Dnm2	RGD:2513 (Rat Genome Database) 25751 (Entrez Gene) Dnm2 (Alliance of Genome Resources)	Chr8 q13			P39052 (UniProt | EBI) NM_013199 (RefSeq)
zebrafish	dnm2a	ZDB-GENE-050913-84 (Zebrafish Model Organism Database) 559334 (Entrez Gene) dnm2a (Alliance of Genome Resources)	Chr3			NP_001025299 (RefSeq) NM_001030128 (RefSeq)
	dnm2b	ZDB-GENE-040426-2371 (Zebrafish Model Organism Database) 406525 (Entrez Gene) dnm2b (Alliance of Genome Resources)	Chr1			NP_998407 (RefSeq) NM_213242 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.