Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DPYD	HGNC:3012 (HGNC) 1806 (Entrez Gene) 612779 (OMIM) DPYD (Alliance of Genome Resources)	Chr1 p21.3	Chr1:97077743-97995000 (-) GRCh38	acute lymphoblastic leukemia dihydropyrimidine dehydrogenase deficiency pancreatic cancer	Q12882 (UniProt | EBI) NM_001160301 (RefSeq)
mouse	Dpyd	MGI:2139667 (MGI) 99586 (Entrez Gene) Gene Tree Dpyd (Alliance of Genome Resources)	Chr3 51.96 cM	Chr3:118355778-119226573 (+) GRCm39		ENSMUSG00000033308 (Ensembl Gene Model) ENSMUSP00000039429 (Ensembl) ENSMUST00000039177 (Ensembl)
rat	Dpyd	RGD:621218 (Rat Genome Database) 81656 (Entrez Gene) Dpyd (Alliance of Genome Resources)	Chr2 q42			O89000 (UniProt | EBI) NM_031027 (RefSeq)
zebrafish	dpyda.1	ZDB-GENE-061013-727 (Zebrafish Model Organism Database) 768165 (Entrez Gene) dpyda.1 (Alliance of Genome Resources)	Chr24			XP_017209335 (RefSeq) NM_001077308 (RefSeq)
	dpydb	ZDB-GENE-040426-2459 (Zebrafish Model Organism Database) 405829 (Entrez Gene) dpydb (Alliance of Genome Resources)	Chr2			Q6NYG8 (UniProt | EBI) NM_212893 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.