Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF2B2	HGNC:3258 (HGNC) 8892 (Entrez Gene) 606454 (OMIM) EIF2B2 (Alliance of Genome Resources)	Chr14 q24.3	Chr14:75002921-75012366 (+) GRCh38	leukoencephalopathy with vanishing white matter leukoencephalopathy with vanishing white matter 2	P49770 (UniProt | EBI) NM_014239 (RefSeq)
mouse	Eif2b2	MGI:2145118 (MGI) 217715 (Entrez Gene) Gene Tree Eif2b2 (Alliance of Genome Resources)	Chr12 39.6 cM	Chr12:85266255-85273402 (+) GRCm39		217715 (NCBI Gene Model) Q99LD9 (UniProt | EBI) NM_145445 (RefSeq)
rat	Eif2b2	RGD:620820 (Rat Genome Database) 84005 (Entrez Gene) Eif2b2 (Alliance of Genome Resources)	Chr6 q31			Q62818 (UniProt | EBI) NM_032058 (RefSeq)
zebrafish	eif2b2	ZDB-GENE-040426-2605 (Zebrafish Model Organism Database) 405839 (Entrez Gene) eif2b2 (Alliance of Genome Resources)	Chr20			NP_998068 (RefSeq) NM_212903 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.