Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GAB1	HGNC:4066 (HGNC) 2549 (Entrez Gene) 604439 (OMIM) GAB1 (Alliance of Genome Resources)	Chr4 q31.21	Chr4:143336876-143474565 (+) GRCh38	autosomal recessive nonsyndromic deafness 26	Q13480 (UniProt | EBI) NM_002039 (RefSeq)
mouse	Gab1	MGI:108088 (MGI) 14388 (Entrez Gene) Gene Tree Gab1 (Alliance of Genome Resources)	Chr8 38.47 cM	Chr8:81491067-81607148 (-) GRCm39		ENSMUSG00000031714 (Ensembl Gene Model) ENSMUSP00000147784 (Ensembl) ENSMUST00000210676 (Ensembl)
rat	Gab1	RGD:1311085 (Rat Genome Database) 361388 (Entrez Gene) Gab1 (Alliance of Genome Resources)	Chr19 q11			NP_001101914 (RefSeq) NM_001108444 (RefSeq)
zebrafish	gab1	ZDB-GENE-040426-2674 (Zebrafish Model Organism Database) 406666 (Entrez Gene) gab1 (Alliance of Genome Resources)	Chr1			NP_001313642 (RefSeq) NM_001326713 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.