Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	UGT1A1	HGNC:12530 (HGNC) 54658 (Entrez Gene) 191740 (OMIM) UGT1A1 (Alliance of Genome Resources)	Chr2 q37.1	Chr2:233760270-233773300 (+) GRCh38	bilirubin metabolic disorder breast cancer cholecystolithiasis cholelithiasis Crigler-Najjar syndrome Crohn's disease endometrial cancer Gilbert syndrome hepatitis B lung non-small cell carcinoma myeloid leukemia ovarian cancer	P22309 (UniProt | EBI) NM_000463 (RefSeq)
mouse	Ugt1a1	MGI:98898 (MGI) 394436 (Entrez Gene) Gene Tree Ugt1a1 (Alliance of Genome Resources)	Chr1 44.55 cM	Chr1:88139681-88146719 (+) GRCm39		ENSMUSG00000089960 (Ensembl Gene Model) ENSMUSP00000072803 (Ensembl) ENSMUST00000073049 (Ensembl)
rat	Ugt1a1	RGD:3935 (Rat Genome Database) 24861 (Entrez Gene) Ugt1a1 (Alliance of Genome Resources)	Chr9 q35			Q64550 (UniProt | EBI) NM_012683 (RefSeq)
zebrafish	ugt1a7	ZDB-GENE-080227-6 (Zebrafish Model Organism Database) 100384891 (Entrez Gene) ugt1a7 (Alliance of Genome Resources)	Chr9			NP_001170805 (RefSeq) NM_001177334 (RefSeq)
	ugt1ab	ZDB-GENE-040426-2762 (Zebrafish Model Organism Database) 406731 (Entrez Gene) ugt1ab (Alliance of Genome Resources)	Chr9			NP_998587 (RefSeq) NM_213422 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.