Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HK1	HGNC:4922 (HGNC) 3098 (Entrez Gene) 142600 (OMIM) HK1 (Alliance of Genome Resources)	Chr10 q22.1	Chr10:69269984-69401884 (+) GRCh38	acute lymphoblastic leukemia anemia Charcot-Marie-Tooth disease type 4G congenital nonspherocytic hemolytic anemia multiple myeloma obesity retinitis pigmentosa	P19367 (UniProt | EBI) NM_001322364 (RefSeq)
mouse	Hk1	MGI:96103 (MGI) 15275 (Entrez Gene) Gene Tree Hk1 (Alliance of Genome Resources)	Chr10 32.37 cM	Chr10:62104634-62215687 (-) GRCm39		ENSMUSG00000037012 (Ensembl Gene Model) ENSMUSP00000111946 (Ensembl) ENSMUST00000116238 (Ensembl)
rat	Hk1	RGD:2796 (Rat Genome Database) 25058 (Entrez Gene) Hk1 (Alliance of Genome Resources)	Chr20 q11			P05708 (UniProt | EBI) NM_012734 (RefSeq)
zebrafish	hk1	ZDB-GENE-040426-2848 (Zebrafish Model Organism Database) 406791 (Entrez Gene) hk1 (Alliance of Genome Resources)	Chr13			NP_998417 (RefSeq) NM_213252 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.