Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KRIT1	HGNC:1573 (HGNC) 889 (Entrez Gene) 604214 (OMIM) KRIT1 (Alliance of Genome Resources)	Chr7 q21.2	Chr7:92197498-92246166 (-) GRCh38	cerebral cavernous malformation cerebral cavernous malformation 1	O00522 (UniProt | EBI) NM_194454 (RefSeq)
mouse	Krit1	MGI:1930618 (MGI) 79264 (Entrez Gene) Gene Tree Krit1 (Alliance of Genome Resources)	Chr5 2.26 cM	Chr5:3853156-3894515 (+) GRCm39	cerebral cavernous malformation	79264 (NCBI Gene Model) Q6S5J6 (UniProt | EBI) NR_033173 (RefSeq)
rat	Krit1	RGD:1305929 (Rat Genome Database) 362317 (Entrez Gene) Krit1 (Alliance of Genome Resources)	Chr4 q13			NP_001102088 (RefSeq) NM_001108618 (RefSeq)
zebrafish	krit1	ZDB-GENE-030131-555 (Zebrafish Model Organism Database) 321836 (Entrez Gene) krit1 (Alliance of Genome Resources)	Chr19			F1REV3 (UniProt | EBI) NM_001317001 (RefSeq)
	lmtk2	ZDB-GENE-100812-11 (Zebrafish Model Organism Database) 564666 (Entrez Gene) lmtk2 (Alliance of Genome Resources)	Chr3			NP_001313401 (RefSeq) NM_001326472 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.