Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MYC	HGNC:7553 (HGNC) 4609 (Entrez Gene) 190080 (OMIM) MYC (Alliance of Genome Resources)	Chr8 q24.21	Chr8:127735434-127742951 (+) GRCh38	acute promyelocytic leukemia angiosarcoma breast cancer Burkitt lymphoma demyelinating disease lung adenocarcinoma prostate adenocarcinoma prostate cancer urinary bladder cancer	P01106 (UniProt | EBI) NM_002467 (RefSeq)
mouse	Myc	MGI:97250 (MGI) 17869 (Entrez Gene) Gene Tree Myc (Alliance of Genome Resources)	Chr15 26.19 cM	Chr15:61857240-61862223 (+) GRCm39	autosomal dominant polycystic kidney disease breast cancer Burkitt lymphoma hepatocellular carcinoma pancreatic carcinoma	ENSMUSG00000022346 (Ensembl Gene Model) ENSMUSP00000022971 (Ensembl) ENSMUST00000022971 (Ensembl)
rat	Myc	RGD:3130 (Rat Genome Database) 24577 (Entrez Gene) Myc (Alliance of Genome Resources)	Chr7 q33			P09416 (UniProt | EBI) NM_012603 (RefSeq)
zebrafish	myca	ZDB-GENE-990415-162 (Zebrafish Model Organism Database) 30686 (Entrez Gene) myca (Alliance of Genome Resources)	Chr24			P52160 (UniProt | EBI) NM_131412 (RefSeq)
	mycb	ZDB-GENE-040426-780 (Zebrafish Model Organism Database) 393141 (Entrez Gene) mycb (Alliance of Genome Resources)	Chr2			Q7ZVS9 (UniProt | EBI) NM_200172 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.