Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PPM1D	HGNC:9277 (HGNC) 8493 (Entrez Gene) 605100 (OMIM) PPM1D (Alliance of Genome Resources)	Chr17 q23.2	Chr17:60600193-60666280 (+) GRCh38	breast cancer	O15297 (UniProt | EBI) NM_003620 (RefSeq)
mouse	Ppm1d	MGI:1858214 (MGI) 53892 (Entrez Gene) Gene Tree Ppm1d (Alliance of Genome Resources)	Chr11 51.34 cM	Chr11:85202080-85237897 (+) GRCm39		53892 (NCBI Gene Model) Q9QZ67 (UniProt | EBI) NM_016910 (RefSeq)
rat	Ppm1d	RGD:1305460 (Rat Genome Database) 287585 (Entrez Gene) Ppm1d (Alliance of Genome Resources)	Chr10 q26			NP_001099295 (RefSeq) NM_001105825 (RefSeq)
zebrafish	ppm1da	ZDB-GENE-040426-815 (Zebrafish Model Organism Database) 394065 (Entrez Gene) ppm1da (Alliance of Genome Resources)	Chr15			NP_957384 (RefSeq) NM_201090 (RefSeq)
	ppm1db	ZDB-GENE-041114-27 (Zebrafish Model Organism Database) 492468 (Entrez Gene) ppm1db (Alliance of Genome Resources)	Chr5			NP_001007341 (RefSeq) NM_001007340 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.