Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EPHX1	HGNC:3401 (HGNC) 2052 (Entrez Gene) 132810 (OMIM) EPHX1 (Alliance of Genome Resources)	Chr1 q42.12	Chr1:225810124-225845563 (+) GRCh38	acute lymphoblastic leukemia acute myeloid leukemia anemia aplastic anemia asbestosis asthma bone disease chronic obstructive pulmonary disease disease of metabolism Leber hereditary optic neuropathy multiple myeloma non-Hodgkin lymphoma Parkinson's disease pre-eclampsia pulmonary emphysema respiratory system disease toxic encephalopathy urinary bladder cancer	P07099 (UniProt | EBI) NM_001136018 (RefSeq)
mouse	Ephx1	MGI:95405 (MGI) 13849 (Entrez Gene) Gene Tree Ephx1 (Alliance of Genome Resources)	Chr1 84.48 cM	Chr1:180817121-180845134 (-) GRCm39		13849 (NCBI Gene Model) Q9D379 (UniProt | EBI) NM_010145 (RefSeq)
rat	Ephx1	RGD:2557 (Rat Genome Database) 25315 (Entrez Gene) Ephx1 (Alliance of Genome Resources)	Chr13 q26			P07687 (UniProt | EBI) NM_001034090 (RefSeq)
zebrafish	ephx1	ZDB-GENE-040426-913 (Zebrafish Model Organism Database) 394043 (Entrez Gene) ephx1 (Alliance of Genome Resources)	Chr20			NP_957362 (RefSeq) NM_201068 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.