Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TNNI3	HGNC:11947 (HGNC) 7137 (Entrez Gene) 191044 (OMIM) TNNI3 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:55151767-55157773 (-) GRCh38	dilated cardiomyopathy dilated cardiomyopathy 1FF dilated cardiomyopathy 2A hypertrophic cardiomyopathy hypertrophic cardiomyopathy 7 restrictive cardiomyopathy restrictive cardiomyopathy 1	P19429 (UniProt | EBI) NM_000363 (RefSeq)
mouse	Tnni3	MGI:98783 (MGI) 21954 (Entrez Gene) Gene Tree Tnni3 (Alliance of Genome Resources)	Chr7 2.61 cM	Chr7:4521304-4526228 (-) GRCm39	hypertrophic cardiomyopathy 7 restrictive cardiomyopathy	21954 (NCBI Gene Model) P48787 (UniProt | EBI) NM_009406 (RefSeq)
rat	Tnni3	RGD:62052 (Rat Genome Database) 29248 (Entrez Gene) Tnni3 (Alliance of Genome Resources)	Chr1 q12			P23693 (UniProt | EBI) NM_017144 (RefSeq)
zebrafish	tnni2a.1	ZDB-GENE-041114-60 (Zebrafish Model Organism Database) 492493 (Entrez Gene) tnni2a.1 (Alliance of Genome Resources)	Chr25			NP_001007366 (RefSeq) NM_001007365 (RefSeq)
	tnni2a.2	ZDB-GENE-040426-970 (Zebrafish Model Organism Database) 394068 (Entrez Gene) tnni2a.2 (Alliance of Genome Resources)	Chr25			NP_001417878 (RefSeq) NM_201093 (RefSeq)
	tnni2a.3	ZDB-GENE-040718-80 (Zebrafish Model Organism Database) 402809 (Entrez Gene) tnni2a.3 (Alliance of Genome Resources)	Chr25			NP_991138 (RefSeq) NM_205575 (RefSeq)
	tnni2a.4	ZDB-GENE-040625-119 (Zebrafish Model Organism Database) 494164 (Entrez Gene) tnni2a.4 (Alliance of Genome Resources)	Chr25			NP_001009901 (RefSeq) NM_001009901 (RefSeq)
	tnni2b.1	ZDB-GENE-050417-49 (Zebrafish Model Organism Database) 550249 (Entrez Gene) tnni2b.1 (Alliance of Genome Resources)	Chr7			NP_001017587 (RefSeq) NM_001017587 (RefSeq)
	tnni2b.2	ZDB-GENE-040801-9 (Zebrafish Model Organism Database) 445029 (Entrez Gene) tnni2b.2 (Alliance of Genome Resources)	Chr7			NP_001003423 (RefSeq) NM_001003423 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.