Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PTH	HGNC:9606 (HGNC) 5741 (Entrez Gene) 168450 (OMIM) PTH (Alliance of Genome Resources)	Chr11 p15.3	Chr11:13492054-13496181 (-) GRCh38	chronic kidney disease familial isolated hypoparathyroidism hyperphosphatemia osteosarcoma secondary hyperparathyroidism type 1 diabetes mellitus type 2 diabetes mellitus	P01270 (UniProt | EBI) NM_000315 (RefSeq)
mouse	Pth	MGI:97799 (MGI) 19226 (Entrez Gene) Gene Tree Pth (Alliance of Genome Resources)	Chr7 59.19 cM	Chr7:112984787-112987777 (-) GRCm39		ENSMUSG00000059077 (Ensembl Gene Model) ENSMUSP00000078723 (Ensembl) ENSMUST00000079793 (Ensembl)
rat	Pth	RGD:3440 (Rat Genome Database) 24694 (Entrez Gene) Pth (Alliance of Genome Resources)	Chr1 q33			P04089 (UniProt | EBI) NM_017044 (RefSeq)
zebrafish	pth1a	ZDB-GENE-040623-1 (Zebrafish Model Organism Database) 405886 (Entrez Gene) pth1a (Alliance of Genome Resources)	Chr25			NP_998115 (RefSeq) NM_212950 (RefSeq)
	pth1b	ZDB-GENE-040623-2 (Zebrafish Model Organism Database) 405885 (Entrez Gene) pth1b (Alliance of Genome Resources)	Chr7			NP_998114 (RefSeq) NM_212949 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.