Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PLS3	HGNC:9091 (HGNC) 5358 (Entrez Gene) 300131 (OMIM) PLS3 (Alliance of Genome Resources)	ChrX q23	ChrX:115561174-115650861 (+) GRCh38	congenital diaphragmatic hernia	P13797 (UniProt | EBI) NM_001172335 (RefSeq)
mouse	Pls3	MGI:104807 (MGI) 102866 (Entrez Gene) Gene Tree Pls3 (Alliance of Genome Resources)	ChrX 38.3 cM	ChrX:74829260-74918788 (-) GRCm39	congenital diaphragmatic hernia osteoporosis	ENSMUSG00000016382 (Ensembl Gene Model) ENSMUSP00000109692 (Ensembl) ENSMUST00000114058 (Ensembl)
rat	Pls3	RGD:621409 (Rat Genome Database) 81748 (Entrez Gene) Pls3 (Alliance of Genome Resources)	ChrX q34			Q63598 (UniProt | EBI) NM_031084 (RefSeq)
zebrafish	pls3	ZDB-GENE-040718-10 (Zebrafish Model Organism Database) 436598 (Entrez Gene) pls3 (Alliance of Genome Resources)	Chr14			NP_001002326 (RefSeq) NM_001002326 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.