Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LCTL	HGNC:15583 (HGNC) 197021 (Entrez Gene) 617060 (OMIM) LCTL (Alliance of Genome Resources)	Chr15 q22.31	Chr15:66547179-66565998 (-) GRCh38		Q6UWM7 (UniProt | EBI) NM_207338 (RefSeq)
mouse	Lctl	MGI:2183549 (MGI) 235435 (Entrez Gene) Gene Tree Lctl (Alliance of Genome Resources)	Chr9 34.5 cM	Chr9:64024429-64045400 (+) GRCm39		ENSMUSG00000032401 (Ensembl Gene Model) ENSMUSP00000034969 (Ensembl) ENSMUST00000034969 (Ensembl)
rat	Lctl	RGD:1305177 (Rat Genome Database) 315750 (Entrez Gene) Lctl (Alliance of Genome Resources)	Chr8 q24			NP_001388063 (RefSeq) NM_001401134 (RefSeq)
zebrafish	lctla	ZDB-GENE-040718-233 (Zebrafish Model Organism Database) 437008 (Entrez Gene) lctla (Alliance of Genome Resources)	Chr7			NP_001002735 (RefSeq) NM_001002735 (RefSeq)
	lctlb	ZDB-GENE-060503-93 (Zebrafish Model Organism Database) 564250 (Entrez Gene) lctlb (Alliance of Genome Resources)	Chr18			NP_001093484 (RefSeq) NM_001100014 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.