Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NR1H4	HGNC:7967 (HGNC) 9971 (Entrez Gene) 603826 (OMIM) NR1H4 (Alliance of Genome Resources)	Chr12 q23.1	Chr12:100473708-100564414 (+) GRCh38	extrahepatic cholestasis hepatocellular carcinoma progressive familial intrahepatic cholestasis 5	Q96RI1 (UniProt | EBI) NM_005123 (RefSeq)
mouse	Nr1h4	MGI:1352464 (MGI) 20186 (Entrez Gene) Gene Tree Nr1h4 (Alliance of Genome Resources)	Chr10 44.98 cM	Chr10:89290096-89369447 (-) GRCm39	hepatocellular carcinoma	ENSMUSG00000047638 (Ensembl Gene Model) ENSMUSP00000100933 (Ensembl) ENSMUST00000105296 (Ensembl)
rat	Nr1h4	RGD:628831 (Rat Genome Database) 60351 (Entrez Gene) Nr1h4 (Alliance of Genome Resources)	Chr7 q13			Q62735 (UniProt | EBI) NM_021745 (RefSeq)
zebrafish	nr1h4	ZDB-GENE-040718-313 (Zebrafish Model Organism Database) 436847 (Entrez Gene) nr1h4 (Alliance of Genome Resources)	Chr18			NP_001002574 (RefSeq) NM_001002574 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.