Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMEM53	HGNC:26186 (HGNC) 79639 (Entrez Gene) 619722 (OMIM) TMEM53 (Alliance of Genome Resources)	Chr1 p34.1	Chr1:44635238-44674481 (-) GRCh38	craniotubular dysplasia Ikegawa type	Q6P2H8 (UniProt | EBI) NM_001300748 (RefSeq)
mouse	Tmem53	MGI:1916027 (MGI) 68777 (Entrez Gene) Gene Tree Tmem53 (Alliance of Genome Resources)	Chr4 53.43 cM	Chr4:117109148-117125779 (+) GRCm39	craniotubular dysplasia Ikegawa type	ENSMUSG00000048772 (Ensembl Gene Model) ENSMUSP00000102042 (Ensembl) ENSMUST00000106434 (Ensembl)
rat	Tmem53	RGD:1307066 (Rat Genome Database) 313529 (Entrez Gene) Tmem53 (Alliance of Genome Resources)	Chr5 q36			NP_001101434 (RefSeq) NM_001107964 (RefSeq)
zebrafish	tmem53	ZDB-GENE-040718-384 (Zebrafish Model Organism Database) 436910 (Entrez Gene) tmem53 (Alliance of Genome Resources)	Chr2			Q6DHN0 (UniProt | EBI) NM_001002637 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.