Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	GATA2	HGNC:4171 (HGNC) 2624 (Entrez Gene) 137295 (OMIM) GATA2 (Alliance of Genome Resources)	Chr3 q21.3	Chr3:128479422-128493201 (-) GRCh38	acute myeloid leukemia depressive disorder immunodeficiency 21 myelodysplastic syndrome myeloid leukemia	P23769 (UniProt | EBI) NM_032638 (RefSeq)
mouse	Gata2	MGI:95662 (MGI) 14461 (Entrez Gene) Gene Tree Gata2 (Alliance of Genome Resources)	Chr6 39.2 cM	Chr6:88170873-88184014 (+) GRCm39		14461 (NCBI Gene Model) O09100 (UniProt | EBI) NM_008090 (RefSeq)
rat	Gata2	RGD:2664 (Rat Genome Database) 25159 (Entrez Gene) Gata2 (Alliance of Genome Resources)	Chr4 q34			Q924Y4 (UniProt | EBI) NM_033442 (RefSeq)
zebrafish	gata2a	ZDB-GENE-980526-260 (Zebrafish Model Organism Database) 30480 (Entrez Gene) gata2a (Alliance of Genome Resources)	Chr11			NP_571308 (RefSeq) NM_131233 (RefSeq)
	gata2b	ZDB-GENE-040718-440 (Zebrafish Model Organism Database) 436962 (Entrez Gene) gata2b (Alliance of Genome Resources)	Chr6			NP_001002689 (RefSeq) NM_001002689 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.