Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	OPHN1	HGNC:8148 (HGNC) 4983 (Entrez Gene) 300127 (OMIM) OPHN1 (Alliance of Genome Resources)	ChrX q12	ChrX:67949349-68433913 (-) GRCh38	X-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance	O60890 (UniProt | EBI) NM_002547 (RefSeq)
mouse	Ophn1	MGI:2151070 (MGI) 94190 (Entrez Gene) Gene Tree Ophn1 (Alliance of Genome Resources)	ChrX 42.94 cM	ChrX:97597883-97934631 (-) GRCm39	syndromic intellectual disability	ENSMUSG00000031214 (Ensembl Gene Model) ENSMUSP00000033560 (Ensembl) ENSMUST00000033560 (Ensembl)
rat	Ophn1	RGD:1563435 (Rat Genome Database) 312108 (Entrez Gene) Ophn1 (Alliance of Genome Resources)	ChrX q22			P0CAX5 (UniProt | EBI) NM_001107848 (RefSeq)
zebrafish	ophn1	ZDB-GENE-040718-464 (Zebrafish Model Organism Database) 436982 (Entrez Gene) ophn1 (Alliance of Genome Resources)	Chr5			XP_068077561 (RefSeq) NM_001002709 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.