Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TRPC6	HGNC:12338 (HGNC) 7225 (Entrez Gene) 603652 (OMIM) TRPC6 (Alliance of Genome Resources)	Chr11 q22.1	Chr11:101451564-101872562 (-) GRCh38	chronic fatigue syndrome focal segmental glomerulosclerosis focal segmental glomerulosclerosis 2 nephrotic syndrome type 2	Q9Y210 (UniProt | EBI) NM_004621 (RefSeq)
mouse	Trpc6	MGI:109523 (MGI) 22068 (Entrez Gene) Gene Tree Trpc6 (Alliance of Genome Resources)	Chr9 2.46 cM	Chr9:8544143-8680742 (+) GRCm39	focal segmental glomerulosclerosis 2	ENSMUSG00000031997 (Ensembl Gene Model) ENSMUSP00000057965 (Ensembl) ENSMUST00000050433 (Ensembl)
rat	Trpc6	RGD:619788 (Rat Genome Database) 89823 (Entrez Gene) Trpc6 (Alliance of Genome Resources)	Chr8 q11			NP_446011 (RefSeq) NM_001429127 (RefSeq)
zebrafish	trpc6a	ZDB-GENE-040724-114 (Zebrafish Model Organism Database) 563989 (Entrez Gene) trpc6a (Alliance of Genome Resources)	Chr21			NP_001025453 (RefSeq) NM_001030282 (RefSeq)
	trpc6b	ZDB-GENE-081030-19 (Zebrafish Model Organism Database) 102725535 (Entrez Gene) trpc6b (Alliance of Genome Resources)	Chr18			XP_002665445 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.