HBB Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	HBB	HGNC:4827 (HGNC) 3043 (Entrez Gene) 141900 (OMIM) HBB (Alliance of Genome Resources)	Chr11 p15.4	Chr11:5225464-5229395 (-) GRCh38	acute chest syndrome alpha thalassemia autosomal dominant beta thalassemia beta thalassemia congenital hemolytic anemia delta beta-thalassemia familial erythrocytosis 6 Heinz body anemia hemoglobin C disease hemoglobinopathy malaria polycythemia sickle cell anemia sickle cell disease	P68871 (UniProt \| EBI) NM_000518 (RefSeq)
human	HBD	HGNC:4829 (HGNC) 3045 (Entrez Gene) 142000 (OMIM) HBD (Alliance of Genome Resources)	Chr11 p15.4	Chr11:5232678-5243657 (-) GRCh38		P02042 (UniProt \| EBI) NM_000519 (RefSeq)
mouse	Hbb-bs	MGI:5474852 (MGI) 100503605 (Entrez Gene) Gene Tree Hbb-bs (Alliance of Genome Resources)	Chr7 Syntenic	Chr7:103475730-103477135 (-) GRCm39		100503605 (NCBI Gene Model) NP_001188320 (RefSeq) NM_001201391 (RefSeq)
rat	Hbb	RGD:2783 (Rat Genome Database) 24440 (Entrez Gene) Hbb (Alliance of Genome Resources)	Chr1 q32			P02091 (UniProt \| EBI) NM_033234 (RefSeq)
	Hbb-bs	RGD:1597422 (Rat Genome Database) 689064 (Entrez Gene) Hbb-bs (Alliance of Genome Resources)	Chr1 q32			P11517 (UniProt \| EBI) NM_001111269 (RefSeq)
	Hbbl1	RGD:2290038 (Rat Genome Database) 100134871 (Entrez Gene) Hbbl1 (Alliance of Genome Resources)	Chr1			P11517 (UniProt \| EBI) NM_001113223 (RefSeq)
zebrafish	hbba2	ZDB-GENE-040801-164 (Zebrafish Model Organism Database) 445037 (Entrez Gene) hbba2 (Alliance of Genome Resources)	Chr3			NP_001003431 (RefSeq) NM_001003431 (RefSeq)