Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PRKACA	HGNC:9380 (HGNC) 5566 (Entrez Gene) 601639 (OMIM) PRKACA (Alliance of Genome Resources)	Chr19 p13.12	Chr19:14091688-14118084 (-) GRCh38	adrenal cortical adenoma congestive heart failure fibrolamellar carcinoma primary pigmented nodular adrenocortical disease 4	P17612 (UniProt | EBI) NM_207518 (RefSeq)
mouse	Prkaca	MGI:97592 (MGI) 18747 (Entrez Gene) Gene Tree Prkaca (Alliance of Genome Resources)	Chr8 40.22 cM	Chr8:84699622-84723072 (+) GRCm39		ENSMUSG00000005469 (Ensembl Gene Model) ENSMUSP00000005606 (Ensembl) ENSMUST00000005606 (Ensembl)
rat	Prkaca	RGD:3389 (Rat Genome Database) 25636 (Entrez Gene) Prkaca (Alliance of Genome Resources)	Chr19 q11			P27791 (UniProt | EBI) NM_001100922 (RefSeq)
zebrafish	prkacaa	ZDB-GENE-050114-6 (Zebrafish Model Organism Database) 564064 (Entrez Gene) prkacaa (Alliance of Genome Resources)	Chr3			NP_001076309 (RefSeq) NM_001082840 (RefSeq)
	prkacab	ZDB-GENE-040801-208 (Zebrafish Model Organism Database) 445076 (Entrez Gene) prkacab (Alliance of Genome Resources)	Chr1			NP_001003470 (RefSeq) NM_001003470 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.