Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	HTRA3	HGNC:30406 (HGNC) 94031 (Entrez Gene) 608785 (OMIM) HTRA3 (Alliance of Genome Resources)	Chr4 p16.1	Chr4:8269754-8307098 (+) GRCh38		P83110 (UniProt | EBI) NM_053044 (RefSeq)
mouse	Htra3	MGI:1925808 (MGI) 78558 (Entrez Gene) Gene Tree Htra3 (Alliance of Genome Resources)	Chr5 18.49 cM	Chr5:35809367-35837126 (-) GRCm39		ENSMUSG00000029096 (Ensembl Gene Model) ENSMUSP00000084910 (Ensembl) ENSMUST00000087629 (Ensembl)
rat	Htra3	RGD:1308120 (Rat Genome Database) 360959 (Entrez Gene) Htra3 (Alliance of Genome Resources)	Chr14 q21			D3ZA76 (UniProt | EBI) NM_001271027 (RefSeq)
zebrafish	htra3a	ZDB-GENE-040801-245 (Zebrafish Model Organism Database) 445108 (Entrez Gene) htra3a (Alliance of Genome Resources)	Chr1			NP_001003502 (RefSeq) NM_001003502 (RefSeq)
	htra3b	ZDB-GENE-110602-1 (Zebrafish Model Organism Database) 573378 (Entrez Gene) htra3b (Alliance of Genome Resources)	Chr7			XP_021333811 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.