Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MEF2C	HGNC:6996 (HGNC) 4208 (Entrez Gene) 600662 (OMIM) MEF2C (Alliance of Genome Resources)	Chr5 q14.3	Chr5:88717117-88904257 (-) GRCh38	neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Q06413 (UniProt | EBI) NM_001364357 (RefSeq)
mouse	Mef2c	MGI:99458 (MGI) 17260 (Entrez Gene) Gene Tree Mef2c (Alliance of Genome Resources)	Chr13 43.68 cM	Chr13:83652153-83815199 (+) GRCm39		ENSMUSG00000005583 (Ensembl Gene Model) ENSMUSP00000132547 (Ensembl) ENSMUST00000163888 (Ensembl)
rat	Mef2c	RGD:1563119 (Rat Genome Database) 499497 (Entrez Gene) Mef2c (Alliance of Genome Resources)	Chr2 q11			A0A096MJY4 (UniProt | EBI) NM_001399399 (RefSeq)
zebrafish	mef2ca	ZDB-GENE-980526-253 (Zebrafish Model Organism Database) 30575 (Entrez Gene) mef2ca (Alliance of Genome Resources)	Chr10			NP_571387 (RefSeq) NM_131312 (RefSeq)
	mef2cb	ZDB-GENE-040901-7 (Zebrafish Model Organism Database) 798771 (Entrez Gene) mef2cb (Alliance of Genome Resources)	Chr5			NP_001124434 (RefSeq) NM_001130962 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.