Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ITGA6	HGNC:6142 (HGNC) 3655 (Entrez Gene) 147556 (OMIM) ITGA6 (Alliance of Genome Resources)	Chr2 q31.1	Chr2:172234216-172506459 (+) GRCh38	junctional epidermolysis bullosa junctional epidermolysis bullosa with pyloric atresia	P23229 (UniProt | EBI) NM_001365529 (RefSeq)
mouse	Itga6	MGI:96605 (MGI) 16403 (Entrez Gene) Gene Tree Itga6 (Alliance of Genome Resources)	Chr2 42.79 cM	Chr2:71617236-71688761 (+) GRCm39	junctional epidermolysis bullosa Herlitz type	16403 (NCBI Gene Model) Q61739 (UniProt | EBI) NM_008397 (RefSeq)
rat	Itga6	RGD:621633 (Rat Genome Database) 114517 (Entrez Gene) Itga6 (Alliance of Genome Resources)	Chr3 q23			NP_446177 (RefSeq) NM_053725 (RefSeq)
zebrafish	itga6a	ZDB-GENE-050309-23 (Zebrafish Model Organism Database) 503893 (Entrez Gene) itga6a (Alliance of Genome Resources)	Chr9			XP_005167466 (RefSeq) NM_001144781 (RefSeq)
	itga6b	ZDB-GENE-050320-5 (Zebrafish Model Organism Database) 541320 (Entrez Gene) itga6b (Alliance of Genome Resources)	Chr1			NP_001013466 (RefSeq) NM_001013448 (RefSeq)
	itga6l	ZDB-GENE-040914-57 (Zebrafish Model Organism Database) 555254 (Entrez Gene) itga6l (Alliance of Genome Resources)	Chr14			XP_021328569 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.