Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADAM10	HGNC:188 (HGNC) 102 (Entrez Gene) 602192 (OMIM) ADAM10 (Alliance of Genome Resources)	Chr15 q21.3	Chr15:58588809-58749791 (-) GRCh38	Alzheimer's disease 18 reticulate acropigmentation of Kitamura	O14672 (UniProt | EBI) NM_001320570 (RefSeq)
mouse	Adam10	MGI:109548 (MGI) 11487 (Entrez Gene) Gene Tree Adam10 (Alliance of Genome Resources)	Chr9 39.53 cM	Chr9:70586279-70687511 (+) GRCm39		ENSMUSG00000054693 (Ensembl Gene Model) ENSMUSP00000063839 (Ensembl) ENSMUST00000067880 (Ensembl)
rat	Adam10	RGD:2032 (Rat Genome Database) 29650 (Entrez Gene) Adam10 (Alliance of Genome Resources)	Chr8 q24			Q10743 (UniProt | EBI) NM_019254 (RefSeq)
zebrafish	adam10a	ZDB-GENE-040917-2 (Zebrafish Model Organism Database) 566044 (Entrez Gene) adam10a (Alliance of Genome Resources)	Chr7			NP_001417916 (RefSeq) NM_001430987 (RefSeq)
	adam10b	ZDB-GENE-071115-1 (Zebrafish Model Organism Database) 393392 (Entrez Gene) adam10b (Alliance of Genome Resources)	Chr25			NP_956714 (RefSeq) NM_200420 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.