Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TTR	HGNC:12405 (HGNC) 7276 (Entrez Gene) 176300 (OMIM) TTR (Alliance of Genome Resources)	Chr18 q12.1	Chr18:31557009-31598833 (+) GRCh38	Alzheimer's disease amyloidosis carpal tunnel syndrome 1 dystransthyretinemic hyperthyroxinemia transthyretin amyloidosis	P02766 (UniProt | EBI) NM_000371 (RefSeq)
mouse	Ttr	MGI:98865 (MGI) 22139 (Entrez Gene) Gene Tree Ttr (Alliance of Genome Resources)	Chr18 11.47 cM	Chr18:20798337-20807378 (+) GRCm39	transthyretin amyloidosis	ENSMUSG00000061808 (Ensembl Gene Model) ENSMUSP00000074783 (Ensembl) ENSMUST00000075312 (Ensembl)
rat	Ttr	RGD:3916 (Rat Genome Database) 24856 (Entrez Gene) Ttr (Alliance of Genome Resources)	Chr18 p12			P02767 (UniProt | EBI) NM_012681 (RefSeq)
zebrafish	ttr	ZDB-GENE-040927-14 (Zebrafish Model Organism Database) 449556 (Entrez Gene) ttr (Alliance of Genome Resources)	Chr20			NP_001005598 (RefSeq) NM_001005598 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.