About   Help   FAQ
Vertebrate Homology
Source
Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)  
Alliance Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
select all deselect all Go
human NLRP3 HGNC:16400 (HGNC)
114548 (Entrez Gene)
606416 (OMIM)
NLRP3 (Alliance of Genome Resources)
Chr1 q44 Chr1:247332331-247449108 (+)
GRCh38
autosomal dominant nonsyndromic deafness 34
CINCA Syndrome
familial cold autoinflammatory syndrome 1
Muckle-Wells syndrome
urticaria
Q96P20 (UniProt | EBI)
NM_001127461 (RefSeq)
mouse Nlrp3 MGI:2653833 (MGI)
216799 (Entrez Gene)
Gene Tree
Nlrp3 (Alliance of Genome Resources)
Chr11 37.73 cM Chr11:59432395-59457781 (+)
GRCm39
CINCA Syndrome
familial cold autoinflammatory syndrome 1
metabolic dysfunction-associated steatotic liver disease
216799 (NCBI Gene Model)
Q8R4B8 (UniProt | EBI)
NM_145827 (RefSeq)
rat Nlrp3 RGD:1308314 (Rat Genome Database)
287362 (Entrez Gene)
Nlrp3 (Alliance of Genome Resources)
Chr10 q22 D4A523 (UniProt | EBI)
NM_001191642 (RefSeq)
zebrafish nlrc3l2 ZDB-GENE-081103-33 (Zebrafish Model Organism Database)
799818 (Entrez Gene)
nlrc3l2 (Alliance of Genome Resources)
Chr4
nlrc6 ZDB-GENE-060421-8264 (Zebrafish Model Organism Database)
678565 (Entrez Gene)
nlrc6 (Alliance of Genome Resources)
Chr1 XP_021333113 (RefSeq)
NM_001040323 (RefSeq)
nlrc7 ZDB-GENE-070912-478 (Zebrafish Model Organism Database)
556007 (Entrez Gene)
nlrc7 (Alliance of Genome Resources)
Chr22 XP_021325236 (RefSeq)
nlrc8 ZDB-GENE-070912-363 (Zebrafish Model Organism Database)
795668 (Entrez Gene)
nlrc8 (Alliance of Genome Resources)
Chr15 XP_021322155 (RefSeq)
nlrc9 ZDB-GENE-070912-362 (Zebrafish Model Organism Database)
570229 (Entrez Gene)
nlrc9 (Alliance of Genome Resources)
Chr15 NP_001410204 (RefSeq)
NM_001423274 (RefSeq)
nlrc10 ZDB-GENE-070424-113 (Zebrafish Model Organism Database)
796740 (Entrez Gene)
nlrc10 (Alliance of Genome Resources)
Chr1 XP_068078242 (RefSeq)
nlrc11 ZDB-GENE-121214-30 (Zebrafish Model Organism Database)
100536895 (Entrez Gene)
nlrc11 (Alliance of Genome Resources)
Chr15 XP_003200133 (RefSeq)
nlrp3 ZDB-GENE-070424-110 (Zebrafish Model Organism Database)
567964 (Entrez Gene)
nlrp3 (Alliance of Genome Resources)
Chr1 XP_068078248 (RefSeq)
si:cabz01069012.2 ZDB-GENE-161017-152 (Zebrafish Model Organism Database)
103910258 (Entrez Gene)
si:cabz01069012.2 (Alliance of Genome Resources)
Chr4 XP_021330978 (RefSeq)
si:ch73-24k9.2 ZDB-GENE-121214-29 (Zebrafish Model Organism Database)
100332228 (Entrez Gene)
si:ch73-24k9.2 (Alliance of Genome Resources)
Chr19 XP_017207901 (RefSeq)
si:ch73-50f9.4 ZDB-GENE-131122-9 (Zebrafish Model Organism Database)
799740 (Entrez Gene)
si:ch73-50f9.4 (Alliance of Genome Resources)
Chr17 NP_001352668 (RefSeq)
NM_001365739 (RefSeq)
si:ch73-168d20.1 ZDB-GENE-121214-44 (Zebrafish Model Organism Database)
795914 (Entrez Gene)
si:ch73-168d20.1 (Alliance of Genome Resources)
Chr23 XP_009295444 (RefSeq)
si:ch73-233m11.2 ZDB-GENE-081104-266 (Zebrafish Model Organism Database)
100331661 (Entrez Gene)
si:ch73-233m11.2 (Alliance of Genome Resources)
Chr8 XP_002663111 (RefSeq)
si:ch73-236c18.2 ZDB-GENE-121214-2 (Zebrafish Model Organism Database)
101884123 (Entrez Gene)
si:ch73-236c18.2 (Alliance of Genome Resources)
Chr1 XP_068078272 (RefSeq)
si:ch73-236c18.5 ZDB-GENE-121213-7 (Zebrafish Model Organism Database)
100334029 (Entrez Gene)
si:ch73-236c18.5 (Alliance of Genome Resources)
Chr1
si:ch73-236c18.7 ZDB-GENE-121214-3 (Zebrafish Model Organism Database)
100333378 (Entrez Gene)
si:ch73-236c18.7 (Alliance of Genome Resources)
Chr1 XP_068076985 (RefSeq)
si:ch211-15j1.1 ZDB-GENE-081031-25 (Zebrafish Model Organism Database)
100148972 (Entrez Gene)
si:ch211-15j1.1 (Alliance of Genome Resources)
Chr1 XP_021333536 (RefSeq)
si:ch211-15j1.3 ZDB-GENE-081031-24 (Zebrafish Model Organism Database)
100149929 (Entrez Gene)
si:ch211-15j1.3 (Alliance of Genome Resources)
Chr1
si:ch211-15j1.4 ZDB-GENE-081031-6 (Zebrafish Model Organism Database)
100149225 (Entrez Gene)
si:ch211-15j1.4 (Alliance of Genome Resources)
Chr1 XP_068078241 (RefSeq)
si:ch211-15j1.5 ZDB-GENE-081031-11 (Zebrafish Model Organism Database)
100148489 (Entrez Gene)
si:ch211-15j1.5 (Alliance of Genome Resources)
Chr1 XP_009293975 (RefSeq)
si:ch211-22k7.9 ZDB-GENE-070424-160 (Zebrafish Model Organism Database)
100006564 (Entrez Gene)
si:ch211-22k7.9 (Alliance of Genome Resources)
Chr4 NP_001119957 (RefSeq)
NM_001126485 (RefSeq)
si:ch211-76m11.3 ZDB-GENE-041210-276 (Zebrafish Model Organism Database)
108183497 (Entrez Gene)
si:ch211-76m11.3 (Alliance of Genome Resources)
Chr4 NP_001353367 (RefSeq)
NM_001366438 (RefSeq)
si:ch211-76m11.8 ZDB-GENE-041210-280 (Zebrafish Model Organism Database)
108183498 (Entrez Gene)
si:ch211-76m11.8 (Alliance of Genome Resources)
Chr4 XP_068076598 (RefSeq)
si:ch211-114l13.1 ZDB-GENE-070424-109 (Zebrafish Model Organism Database)
566121 (Entrez Gene)
si:ch211-114l13.1 (Alliance of Genome Resources)
Chr1
si:ch211-114l13.13 ZDB-GENE-120215-237 (Zebrafish Model Organism Database)
567675 (Entrez Gene)
si:ch211-114l13.13 (Alliance of Genome Resources)
Chr1 NP_001315367 (RefSeq)
NM_001328438 (RefSeq)
si:ch211-133h13.1 ZDB-GENE-141215-1 (Zebrafish Model Organism Database)
108184000 (Entrez Gene)
si:ch211-133h13.1 (Alliance of Genome Resources)
Chr4 XP_017211266 (RefSeq)
si:ch211-149a19.3 ZDB-GENE-081104-128 (Zebrafish Model Organism Database)
568118 (Entrez Gene)
si:ch211-149a19.3 (Alliance of Genome Resources)
Chr19 XP_021323904 (RefSeq)
si:ch211-171l17.4 ZDB-GENE-050208-534 (Zebrafish Model Organism Database)
100005625 (Entrez Gene)
si:ch211-171l17.4 (Alliance of Genome Resources)
Chr4 XP_017210866 (RefSeq)
si:ch211-181d7.1 ZDB-GENE-121214-14 (Zebrafish Model Organism Database)
100149909 (Entrez Gene)
si:ch211-181d7.1 (Alliance of Genome Resources)
Chr15 XP_021322168 (RefSeq)
si:ch211-187g4.1 ZDB-GENE-070912-161 (Zebrafish Model Organism Database)
110437934 (Entrez Gene)
si:ch211-187g4.1 (Alliance of Genome Resources)
Chr15 NP_001410195 (RefSeq)
NM_001423266 (RefSeq)
si:ch211-191a16.2 ZDB-GENE-081028-45 (Zebrafish Model Organism Database)
798095 (Entrez Gene)
si:ch211-191a16.2 (Alliance of Genome Resources)
Chr15 XP_001338550 (RefSeq)
si:ch211-191a16.5 ZDB-GENE-121214-56 (Zebrafish Model Organism Database)
569505 (Entrez Gene)
si:ch211-191a16.5 (Alliance of Genome Resources)
Chr15 XP_017206749 (RefSeq)
si:ch211-194e1.7 ZDB-GENE-081105-104 (Zebrafish Model Organism Database)
565044 (Entrez Gene)
si:ch211-194e1.7 (Alliance of Genome Resources)
Chr8 XP_021334175 (RefSeq)
si:ch211-194e1.9 ZDB-GENE-081105-109 (Zebrafish Model Organism Database)
798674 (Entrez Gene)
si:ch211-194e1.9 (Alliance of Genome Resources)
Chr8 XP_017213032 (RefSeq)
si:ch211-196h16.5 ZDB-GENE-081029-8 (Zebrafish Model Organism Database)
561595 (Entrez Gene)
si:ch211-196h16.5 (Alliance of Genome Resources)
Chr1 XP_690098 (RefSeq)
si:ch211-196h24.1 ZDB-GENE-081103-12 (Zebrafish Model Organism Database)
103910692 (Entrez Gene)
si:ch211-196h24.1 (Alliance of Genome Resources)
Chr4
si:ch211-197e7.1 ZDB-GENE-081103-26 (Zebrafish Model Organism Database)
100331576 (Entrez Gene)
si:ch211-197e7.1 (Alliance of Genome Resources)
Chr4 XP_068076236 (RefSeq)
si:ch211-201o1.1 ZDB-GENE-120709-60 (Zebrafish Model Organism Database)
100535360 (Entrez Gene)
si:ch211-201o1.1 (Alliance of Genome Resources)
Chr16 XP_003200157 (RefSeq)
si:ch211-203c5.3 ZDB-GENE-131118-8 (Zebrafish Model Organism Database)
110439605 (Entrez Gene)
si:ch211-203c5.3 (Alliance of Genome Resources)
Chr4 XP_021331412 (RefSeq)
si:ch211-205a14.1 ZDB-GENE-050420-271 (Zebrafish Model Organism Database)
100034571 (Entrez Gene)
si:ch211-205a14.1 (Alliance of Genome Resources)
Chr4
si:ch211-207e19.2 ZDB-GENE-041210-227 (Zebrafish Model Organism Database)
565475 (Entrez Gene)
si:ch211-207e19.2 (Alliance of Genome Resources)
Chr4 XP_017210847 (RefSeq)
si:ch211-213a13.9 ZDB-GENE-050208-632 (Zebrafish Model Organism Database)
569389 (Entrez Gene)
si:ch211-213a13.9 (Alliance of Genome Resources)
Chr22 XP_021325112 (RefSeq)
si:ch211-214b16.3 ZDB-GENE-081105-50 (Zebrafish Model Organism Database)
564346 (Entrez Gene)
si:ch211-214b16.3 (Alliance of Genome Resources)
Chr3 XP_068075553 (RefSeq)
si:ch211-226o13.1 ZDB-GENE-081104-491 (Zebrafish Model Organism Database)
101886579 (Entrez Gene)
si:ch211-226o13.1 (Alliance of Genome Resources)
Chr4 XP_068076150 (RefSeq)
si:ch211-227e10.6 ZDB-GENE-050420-355 (Zebrafish Model Organism Database)
100008037 (Entrez Gene)
si:ch211-227e10.6 (Alliance of Genome Resources)
Chr4 NP_001121772 (RefSeq)
NM_001128300 (RefSeq)
si:ch211-227p7.5 ZDB-GENE-120703-10 (Zebrafish Model Organism Database)
101882512 (Entrez Gene)
si:ch211-227p7.5 (Alliance of Genome Resources)
Chr4 XP_068076584 (RefSeq)
si:ch211-232d10.1 ZDB-GENE-081103-11 (Zebrafish Model Organism Database)
108183520 (Entrez Gene)
si:ch211-232d10.1 (Alliance of Genome Resources)
Chr4 XP_017210912 (RefSeq)
si:ch211-233m11.1 ZDB-GENE-081028-16 (Zebrafish Model Organism Database)
558788 (Entrez Gene)
si:ch211-233m11.1 (Alliance of Genome Resources)
Chr13 XP_005156549 (RefSeq)
si:ch211-236p5.2 ZDB-GENE-081028-33 (Zebrafish Model Organism Database)
561457 (Entrez Gene)
si:ch211-236p5.2 (Alliance of Genome Resources)
Chr17 XP_005158670 (RefSeq)
si:ch211-236p5.3 ZDB-GENE-081028-31 (Zebrafish Model Organism Database)
100002266 (Entrez Gene)
si:ch211-236p5.3 (Alliance of Genome Resources)
Chr17 XP_068070626 (RefSeq)
si:ch211-237a4.2 ZDB-GENE-060503-504 (Zebrafish Model Organism Database)
100034537 (Entrez Gene)
si:ch211-237a4.2 (Alliance of Genome Resources)
Chr4 XP_017211173 (RefSeq)
si:ch211-238e22.8 ZDB-GENE-050419-231 (Zebrafish Model Organism Database)
100007771 (Entrez Gene)
si:ch211-238e22.8 (Alliance of Genome Resources)
Chr4
si:ch211-250k18.7 ZDB-GENE-070912-246 (Zebrafish Model Organism Database)
558026 (Entrez Gene)
si:ch211-250k18.7 (Alliance of Genome Resources)
Chr22 XP_068072662 (RefSeq)
si:ch211-255g12.8 ZDB-GENE-081104-39 (Zebrafish Model Organism Database)
565945 (Entrez Gene)
si:ch211-255g12.8 (Alliance of Genome Resources)
Chr8 XP_009302019 (RefSeq)
si:ch211-271g18.1 ZDB-GENE-081103-38 (Zebrafish Model Organism Database)
100331319 (Entrez Gene)
si:ch211-271g18.1 (Alliance of Genome Resources)
Chr4 XP_017211037 (RefSeq)
si:ch211-278p9.1 ZDB-GENE-081028-46 (Zebrafish Model Organism Database)
101885212 (Entrez Gene)
si:ch211-278p9.1 (Alliance of Genome Resources)
Chr17 NP_001353306 (RefSeq)
NM_001366377 (RefSeq)
si:dkey-11n14.1 ZDB-GENE-060503-332 (Zebrafish Model Organism Database)
100534940 (Entrez Gene)
si:dkey-11n14.1 (Alliance of Genome Resources)
Chr4 XP_068075926 (RefSeq)
si:dkey-23k10.2 ZDB-GENE-131122-52 (Zebrafish Model Organism Database)
565381 (Entrez Gene)
si:dkey-23k10.2 (Alliance of Genome Resources)
Chr15 XP_017206561 (RefSeq)
si:dkey-26m3.3 ZDB-GENE-070705-445 (Zebrafish Model Organism Database)
100148609 (Entrez Gene)
si:dkey-26m3.3 (Alliance of Genome Resources)
Chr4 XP_068076149 (RefSeq)
si:dkey-27n6.1 ZDB-GENE-041014-40 (Zebrafish Model Organism Database)
100034375 (Entrez Gene)
si:dkey-27n6.1 (Alliance of Genome Resources)
Chr4 NP_001137523 (RefSeq)
NM_001144051 (RefSeq)
si:dkey-29j8.1 ZDB-GENE-110913-11 (Zebrafish Model Organism Database)
100334221 (Entrez Gene)
si:dkey-29j8.1 (Alliance of Genome Resources)
Chr4 XP_068076225 (RefSeq)
si:dkey-51d8.1 ZDB-GENE-081103-14 (Zebrafish Model Organism Database)
108183673 (Entrez Gene)
si:dkey-51d8.1 (Alliance of Genome Resources)
Chr4 NP_001410466 (RefSeq)
NM_001423537 (RefSeq)
si:dkey-61p9.9 ZDB-GENE-041210-240 (Zebrafish Model Organism Database)
558818 (Entrez Gene)
si:dkey-61p9.9 (Alliance of Genome Resources)
Chr4 NP_001038341 (RefSeq)
NM_001044876 (RefSeq)
si:dkey-71l4.4 ZDB-GENE-060503-457 (Zebrafish Model Organism Database)
797610 (Entrez Gene)
si:dkey-71l4.4 (Alliance of Genome Resources)
Chr4 NP_001107787 (RefSeq)
NM_001114315 (RefSeq)
si:dkey-121n8.7 ZDB-GENE-070912-366 (Zebrafish Model Organism Database)
108179098 (Entrez Gene)
si:dkey-121n8.7 (Alliance of Genome Resources)
Chr15 XP_009290195 (RefSeq)
si:dkey-124l13.1 ZDB-GENE-141215-10 (Zebrafish Model Organism Database)
101884884 (Entrez Gene)
si:dkey-124l13.1 (Alliance of Genome Resources)
Chr4 XP_021331210 (RefSeq)
si:dkey-151g22.1 ZDB-GENE-041001-115 (Zebrafish Model Organism Database)
564402 (Entrez Gene)
si:dkey-151g22.1 (Alliance of Genome Resources)
Chr4 NP_001137518 (RefSeq)
NM_001144046 (RefSeq)
si:dkey-165e24.1 ZDB-GENE-081103-19 (Zebrafish Model Organism Database)
101884333 (Entrez Gene)
si:dkey-165e24.1 (Alliance of Genome Resources)
Chr4 XP_017211145 (RefSeq)
si:dkey-165o8.1 ZDB-GENE-131118-7 (Zebrafish Model Organism Database)
108183519 (Entrez Gene)
si:dkey-165o8.1 (Alliance of Genome Resources)
Chr4 XP_021330990 (RefSeq)
si:dkey-178j11.5 ZDB-GENE-131118-10 (Zebrafish Model Organism Database)
103910482 (Entrez Gene)
si:dkey-178j11.5 (Alliance of Genome Resources)
Chr4 XP_017210814 (RefSeq)
si:dkey-193i10.4 ZDB-GENE-070705-343 (Zebrafish Model Organism Database)
101884563 (Entrez Gene)
si:dkey-193i10.4 (Alliance of Genome Resources)
Chr4 XP_017210881 (RefSeq)
si:dkey-222h21.1 ZDB-GENE-081031-21 (Zebrafish Model Organism Database)
794765 (Entrez Gene)
si:dkey-222h21.1 (Alliance of Genome Resources)
Chr1 XP_009294058 (RefSeq)
si:dkey-222h21.2 ZDB-GENE-081031-20 (Zebrafish Model Organism Database)
794894 (Entrez Gene)
si:dkey-222h21.2 (Alliance of Genome Resources)
Chr1
si:dkey-222h21.3 ZDB-GENE-081031-31 (Zebrafish Model Organism Database)
795109 (Entrez Gene)
si:dkey-222h21.3 (Alliance of Genome Resources)
Chr1 XP_001335224 (RefSeq)
si:dkey-222h21.7 ZDB-GENE-081031-33 (Zebrafish Model Organism Database)
100332268 (Entrez Gene)
si:dkey-222h21.7 (Alliance of Genome Resources)
Chr1 XP_021333583 (RefSeq)
si:dkey-222h21.8 ZDB-GENE-081031-103 (Zebrafish Model Organism Database)
795597 (Entrez Gene)
si:dkey-222h21.8 (Alliance of Genome Resources)
Chr1
si:dkey-222h21.9 ZDB-GENE-081031-10 (Zebrafish Model Organism Database)
795805 (Entrez Gene)
si:dkey-222h21.9 (Alliance of Genome Resources)
Chr1 XP_068078251 (RefSeq)
si:dkey-222h21.10 ZDB-GENE-081031-22 (Zebrafish Model Organism Database)
100331993 (Entrez Gene)
si:dkey-222h21.10 (Alliance of Genome Resources)
Chr1 XP_017212337 (RefSeq)
si:dkey-222h21.11 ZDB-GENE-081031-32 (Zebrafish Model Organism Database)
103909520 (Entrez Gene)
si:dkey-222h21.11 (Alliance of Genome Resources)
Chr1 XP_009294248 (RefSeq)
si:dkey-233e3.2 ZDB-GENE-070705-388 (Zebrafish Model Organism Database)
560084 (Entrez Gene)
si:dkey-233e3.2 (Alliance of Genome Resources)
Chr4 NP_001116723 (RefSeq)
NM_001123251 (RefSeq)
si:dkey-264f17.2 ZDB-GENE-110913-14 (Zebrafish Model Organism Database)
103910943 (Entrez Gene)
si:dkey-264f17.2 (Alliance of Genome Resources)
Chr4 XP_068076582 (RefSeq)
si:dkeyp-4c4.1 ZDB-GENE-081104-4 (Zebrafish Model Organism Database)
571990 (Entrez Gene)
si:dkeyp-4c4.1 (Alliance of Genome Resources)
Chr4 NP_001094426 (RefSeq)
NM_001100956 (RefSeq)
si:dkeyp-35e5.5 ZDB-GENE-050420-335 (Zebrafish Model Organism Database)
565490 (Entrez Gene)
si:dkeyp-35e5.5 (Alliance of Genome Resources)
Chr4 XP_693868 (RefSeq)
si:dkeyp-100h4.1 ZDB-GENE-081103-7 (Zebrafish Model Organism Database)
103910657 (Entrez Gene)
si:dkeyp-100h4.1 (Alliance of Genome Resources)
Chr4 XP_068076155 (RefSeq)
si:rp71-7l19.2 ZDB-GENE-081103-31 (Zebrafish Model Organism Database)
100000651 (Entrez Gene)
si:rp71-7l19.2 (Alliance of Genome Resources)
Chr4 XP_009298762 (RefSeq)
si:zfos-364h11.1 ZDB-GENE-121214-26 (Zebrafish Model Organism Database)
100333695 (Entrez Gene)
si:zfos-364h11.1 (Alliance of Genome Resources)
Chr17 XP_017207225 (RefSeq)
zgc:110171 ZDB-GENE-050417-391 (Zebrafish Model Organism Database)
550543 (Entrez Gene)
zgc:110171 (Alliance of Genome Resources)
Chr4 NM_001017845 (RefSeq)
zgc:173709 ZDB-GENE-080208-5 (Zebrafish Model Organism Database)
100002234 (Entrez Gene)
zgc:173709 (Alliance of Genome Resources)
Chr4 NP_001373791 (RefSeq)
NM_001110122 (RefSeq)
zgc:174180 ZDB-GENE-080206-1 (Zebrafish Model Organism Database)
100008100 (Entrez Gene)
zgc:174180 (Alliance of Genome Resources)
Chr4 NP_001104724 (RefSeq)
NM_001111254 (RefSeq)
zgc:194906 ZDB-GENE-080722-43 (Zebrafish Model Organism Database)
100170839 (Entrez Gene)
zgc:194906 (Alliance of Genome Resources)
Chr1 NP_001124145 (RefSeq)
NM_001130673 (RefSeq)
zmp:0000001020 ZDB-GENE-130530-1023 (Zebrafish Model Organism Database)
100331680 (Entrez Gene)
zmp:0000001020 (Alliance of Genome Resources)
Chr4 XP_068076929 (RefSeq)
Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory